Gwenael Piganeau



Title : CNRS Research Fellow

Team : Genomics of picophytoplankton

Address : Observatoire Oceanologique de Banyuls sur mer
Laboratoire Arago, Av. de Fontaule, BP 44, 66651 Banyuls-sur-Mer Cedex, France.

Phone No : +33 (0)4 68 88 73 43

Email : gwenael.piganeau@obs-banyuls.fr

Research project :

Evolutionary and Environmental Genomics of Prasinophytes

Summary :

My general research interests concern the mechanisms of genome evolution in eukaryotes. I am using and developing bioinformatic tools to address following issues : What can sequence data (in a broad sense, from complete genomes to metagenomes) tell us about the lifestyle, life-cycle and life history of an organism? This is particulary relevant for planktonic species, because most planktonic species resist cultivation, so that the analysis of their genome is the only information that can be gained into their diversity and lifestyle.

PUBLICATIONS :

Vaulot, D., Lepère, C., Toulza, E., De la Iglesia, R., Poulain, J., Gaboyer, F., Moreau, H, Vandepoele, K, Ulloa, O., Gavory, F. and G. Piganeau (2012) Metagenomes of the picoalga Bathycoccus from the Chile upwelling. PLoS one. 7(6):e39648.

Moreau, H., B. Verhelst, A. Couloux, E. Derelle, S. Rombauts, N. Grimsley, M. Van Bel, J. Poulain, M. Katinka, M. F. Hohmann-Marriott, Piganeau G, P. Rouze, C. Da Silva, P. Wincker, Y. Van de Peer, and K. Vandepoele. (2012) Gene functionalities and genome structure in Bathycoccus prasinos reflect cellular specializations at the base of the green lineage. Genome Biol. 13:R74.

Toulza E, Blanc-Mathieu R, Gourbiere S and G. Piganeau (2012) Environmental and Evolutionary Genomics of Microbial Algae: Power and Challenges of Metagenomics. Advances in Botanical Research. 64 : 383-427.

Toulza E, Tagliabue A, Blain S and G. Piganeau (2012) Analysis of the Global Ocean Sampling (GOS) Project for Trends in Iron Uptake by Surface Ocean Microbes. PLoS one. 7(2) :e30931

Piganeau G, Grimsley N and H Moreau. (2011) Genome Diversity In The Smallest Marine Photosynthetic Eukaryotes. Research in Microbiology. 162(6):570-7.

Karsenti E. and the Tara Oceans Consortium. (2011) A holistic approach to marine eco-systems biology. PLoS Biol. 9: e1001177.

Piganeau G, Eyre-Walker A, Grimsley N, Moreau H (2011) How and why DNA barcodes underestimate the diversity of microbial eukaryotes. PLoS one. 6(2): e16342.

Moreau H, Piganeau G, Desdevises Y, Cooke R, Derelle E, Grimsley N. (2010) Marine prasinovirus genomes show low evolutionary divergence and acquisition of protein metabolism genes by horizontal gene transfer. J Virology. 84(24):12555-63.

Grimsley N, Pequin B, Bachy C, Moreau H and G Piganeau. Cryptic sex in the smallest marine green alga. Mol. Biol. Evol. 27(1):47-54.

Piganeau G, Vandepoele K, Gourbiere S, Y van de Peer and H Moreau. Unravelling cis-regulatory elements in the genome of the smallest photosynthetic eukaryote: phylogenetic footprinting in Ostreococcus. J. Mol. Evol. 69(3) :249-52.

Piganeau G and A Eyre-Walker (2009) Evidence for Variation in the Effective Population Size of Animal Mitochondrial DNA. PLoS one. 4(2): e4396.

Jancek S, Gourbiere S, Moreau H and G Piganeau (2008) Clues about the Genetic basis of adaptation emerge from comparing the proteomes of two Ostreococcus ecotypes (Chlorophyta, Prasinophyceae). Mol Biol Evol. 25(11):2293-300.

Piganeau G, Desdevises Y, Derelle E, Moreau H (2008) Picoeukaryotic sequences in the Sargasso sea metagenome. Genome Biology 9:R5.

Derelle E, Ferraz C, Escande ML, Eychenie S, Cooke R, Piganeau G, Desdevises Y, Bellec L, Moreau H, Grimsley N. (2008) Life-cycle and genome of OtV5, a large DNA virus of the pelagic marine unicellular green alga Ostreococcus tauri. PLoS ONE. 3(5):e2250.

Piganeau G, Moreau H (2007) Screening the Sargasso Sea metagenome for data to investigate genome evolution in Ostreococcus (Prasinophyceae, Chlorophyta). Gene 406:184-190.

Palenik B, Grimwood J, Aerts A, Rouze P, Salamov A, Putnam N, Dupont C, Jorgensen R, Derelle E, Rombauts S, Zhou K, Otillar R, Merchant SS, Podell S, Gaasterland T, Napoli C, Gendler K, Manuell A, Tai V, Vallon O, Piganeau G, Jancek S, Heijde M, Jabbari K, Bowler C, Lohr M, Robbens S, Werner G, Dubchak I, Pazour GJ, Ren Q, Paulsen I, Delwiche C, Schmutz J, Rokhsar D, Van de Peer Y, Moreau H, Grigoriev IV (2007) The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation. Proc Natl Acad Sci U S A 104:7705-10.

Derelle E, Ferraz C, Rombauts S, Rouze P, Worden AZ, Robbens S, Partensky F, Degroeve S, Echeynie S, Cooke R, Saeys Y, Wuyts J, Jabbari K, Bowler C, Panaud O, Piegu B, Ball SG, Ral JP, Bouget FY, Piganeau G, De Baets B, Picard A, Delseny M, Demaille J, Van de Peer Y, Moreau H (2006) Genome analysis of the smallest free-living eukaryote Ostreococcus tauri unveils many unique features. Proc Natl Acad Sci U S A 103:11647-52.

Belle EM, Piganeau G, Gardner M, Eyre-Walker A (2005) An investigation of the variation in the transition bias among various animal mitochondrial DNA. Gene 355:58-66.

G. Piganeau, Gardner M and A. Eyre-Walker. (2004) A broad survey of recombination in animal mitochondria. Mol Biol Evol 21(12):2319-25.

J. M. Burrows, L. Bromham, M. Woolfit, G. Piganeau, J. Tellam, G. Connolly, N. Webb, L. Poulsen, L. Cooper, S. Burrows,D. Moss, S. Haryana, M. Ngm J. Nichols and R. Khanna. 2004. Selection Pressure-Driven Evolution of the Epstein-Barr Virus-Encoded Oncogene LMP1 in Virus Isolates from Southease Asia. Journal of Virology, 78:7131-7.

Piganeau G and A Eyre-Walker. 2004. A reanalysis of the relationship between linkage disequilibrium and distance in human mitochondria. Heredity 92(4):282-8.

Piganeau G and A Eyre-Walker. 2003. Inferring the strength of selection acting on amino acid composition. Proceedings of the National Academy of Science 100(18) : 10335-10340.

Duret L, Semon M, Piganeau G, Mouchiroud D, N Galtier. 2003. Vanishing isochores in mammalian genomes. Genetics 162 :1837-1847.

Marais G, Piganeau G. 2002 Hill-Robertson interference is a minor determinant of variations in codon bias across Drosophila melanogaster and Caenorhabditis elegans genomes. Mol Biol Evol. Sep;19(9):1399-406.

Piganeau G, Mouchiroud D, Duret L, Gautier C. 2002 Expected relationship between the silent substitution rate and the GC content: implications for the evolution of isochores. J Mol Evol. Jan;54(1):129-33.

Piganeau G, Westrelin R, Tourancheau B, Gautier C. 2001 Multiplicative versus additive selection in relation to genome evolution: a simulation study. Genet Res. 78(2):171-5.

Galtier N, Piganeau G, Mouchiroud D, Duret L. 2001 GC-content evolution in mammalian genomes: the biased gene conversion hypothesis. Genetics. 159(2):907-11

Vieira C, Piganeau G, Biemont C. 2000 High copy numbers of multiple transposable element families in an Australian population of Drosophila simulans. Genet Res. Aug;76(1):117-9.

TEACHING :

Metagenomics Insights Into Plankton Diversity. Janvier 2011, Module "Genetique et Evolution des Organismes Marins", Sete.

Evolution et Genomique marine : le point de vue picoeukaryote. Fevrier 2009, Module "Genetique et Evolution des Organismes Marins", Sete.

Introduction to bioinformatics : from sequence retrieval to sequence analysis. January 2008, invited Professor at the university of Yucatan, Merida, Mexico.

Evolution of base composition, lecture, university of Perpignan Via Domitia.